Clinical Research Nurse - Cancer Center

Saint Louis University is a nationally recognized R1 research university, placing it among the top research institutions in the nation. Through innovative clinical research and academic excellence, SLU investigators are advancing new treatments, technologies, and standards of care that improve patient outcomes and transform healthcare.

The Cancer Centeris seeking a Clinical Research Nurse to support a growing portfolio of clinical research studies. This position offers the opportunity to contribute to high-impact clinical research while leveraging nursing expertise in a role that focuses on study coordination, regulatory compliance, participant oversight, and research operations.

The Clinical Research Nurse will use their clinical knowledge and judgment to review study activities, ensure participant safety requirements are met, interpret protocol requirements, and coordinate research-related procedures. While nursing expertise is essential, this role is primarily focused on research operations and study management rather than direct patient care.

Due to the nature of clinical trial activation and enrollment timelines, there may be an initial period focused heavily on study startup, regulatory activities, protocol review, and research administration before study enrollment activity increases. Over time, the Clinical Research Nurse will build and manage a portfolio of active research studies.

Why Join Saint Louis University?

Benefits include:

• Monday-Friday schedule, (5 - 8 Hour Shifts/week)

• Flexible work schedulesavailable based on department needs

• 15 vacation days,13 sick days,10+ paid holidays each year

• Tuition remission for employees and eligible dependents

• Comprehensive medical, dental, vision, and retirement benefits

• Collaborative environment with opportunities for professional growth and development

• Saint Louis University offers the opportunity to combine patient care with scientific advancement while enjoying a strong work-life balance and exceptional benefits

Key Responsibilities

• Coordinate research studies from startup through study completion.

• Review protocols and study documentation to ensure appropriate clinical implementation.

• Monitor study progress and ensure protocol requirements are completed accurately and on schedule.

• Collaborate with investigators, sponsors, clinical staff, and research team members to support study conduct.

• Serve as a clinical resource for research teams regarding protocol requirements and participant safety considerations.

• Ensure study activities comply with Good Clinical Practice (GCP), institutional policies, and regulatory requirements.

• Apply nursing knowledge to evaluate study procedures and ensure participant care requirements are appropriately addressed.

• Provide guidance and coordination to clinical staff performing protocol-related procedures.

• Collaborate closely with SSM clinical teams to facilitate study activities.

• Review participant eligibility, clinical documentation, laboratory results, and protocol requirements.

• Identify and escalate participant safety concerns, protocol deviations, and adverse events when appropriate.

• Maintain study records, regulatory binders, and required study documentation and correspondence.

• Support study startup activities, regulatory submissions, and ongoing compliance requirements.

• Prepare for sponsor monitoring visits, audits, and inspections.

• Ensure accurate and timely documentation of all research-related activities.

• Other duties as assigned.

Knowledge, Skills, and Abilities

• Strong understanding of clinical nursing practice and ability to apply clinical judgment within a research setting.

• Exceptional attention to detail and organizational skills.

• Ability to review and interpret complex data and information.

• Strong written and verbal communication skills.

• Ability to work independently and manage multiple priorities.

• Collaborative approach to working with investigators, sponsors, and clinical teams.

• Strong computer proficiency and comfort working within multiple electronic systems.

• Ability to thrive in a structured, process-driven environment.

• Minimum Qualifications

• Registered Nurse (RN) with current Missouri nursing license or eligibility for Missouri licensure.

• Current BLS certification.

• Minimum of three years of professional nursing experience.

• Experience utilizing electronic medical records and Microsoft Office applications.

Preferred Qualifications

• Clinical research or clinical trials experience.

• Oncology, critical care, acute care, hospital-based, or specialty nursing experience.

• Experience interpreting clinical documentation, laboratory data, and treatment plans.

• Demonstrated ability to work independently and manage complex processes.

What Success Looks Like

The ideal candidate is a nurse who enjoys the analytical and operational side of healthcare and is interested in applying their clinical expertise beyond direct bedside care. They are highly organized, detail-oriented, and comfortable managing documentation, reviewing protocols, coordinating study activities, and working collaboratively across multiple teams.

This role is particularly well suited for nurses seeking a transition from direct patient care into clinical research, regulatory operations, or study management while continuing to play an important role in advancing medical discoveries and improving patient outcomes through research.