Clinical Genomic Technologist II

The Clinical Genomics Technologist II will be responsible for processing both clinical and research samples using cutting-edge technologies for multi-omic analysis, including but not limited to PCR, next-generation sequencing, arrays, and long-read sequencing technologies. These activities will be performed under CLIA/CAP regulations and will directly impact human health and thus must meet the highest possible standards for quality and integrity. The Clinical Genomics Technologist I, II, or III are distinguishable primarily by level of experience, supervision required, proficiency in problem solving, certification and wider range of training.

Key Responsibilities & Essential Functions

• This position is a split role between the JAX Advanced Precision Medicine Laboratory (APML), a CLIA-certified and CAP-accredited laboratory, and the Genome Technologies (GT) sequencing core at The Jackson Laboratory for Genomic Medicine. These groups share laboratory space and equipment but operate independently to fulfill clinical and research customer needs, respectively. The technologist in this role is anticipated to spend an average of 50% effort with each team.
• This role is responsible for the efficient and quality execution of research and clinical sample accessioning, processing, and data generation for the Advanced Precision Medicine Laboratory. This includes:
  • Working with the Supervisor to maintain all documentation required for operation under CLIA/CAP certification, including review and writing of SOPs as necessary and use of sample tracking systems in accordance with standard operating procedures.
  • Timely completion of training assigned by management or CLD to meet the needs of laboratory operations.
  • Ensuring sample accessioning is performed in an accurate manner to enable effective testing of samples downstream as ordered.
  • Working with lab pathologist to evaluate neoplastic content of samples as needed.
  • Sample processing including nucleic acid purification and QC, PCR, library preparation, and sequencing per established processes.
  • Accurate and timely maintenance of operational metrics.
  • Participating in continuous process improvements and ongoing training.
  • Maintenance of auxiliary and capital equipment and instrumentation as delegated.
  • Development and validation of new methodologies, including establishing novel workflows and evaluating new instrumentation and protocols as deemed necessary by the clinical laboratory manager and/or director.
  • Making technological/scientific contributions to development projects.
  • Researching, evaluating, and implementing new and emerging applications and tools to improve current clinical offerings and to support new clinical offerings.
• This role is responsible for executing laboratory processes and generating genomic sequencing data within the Genome Technologies core.
  • Perform a wide range of genomic laboratory productional procedures, including DNA/RNA extraction, library preparation, target enrichment, and sequencing, for the generation and delivery of NGS data
  • Operate and maintain genomic instruments and equipment, ensuring their proper functioning
  • Troubleshoot to solve problems as they arise
  • Execute quality control (QC) measures and ensure compliance with standard operating procedures (SOPs) and accurate and reliable results
  • Collaborate with team members to optimize experimental protocols, troubleshoot technical challenges, and improve workflows
  • Develop cost structure for new service deliverables
  • Keep accurate and detailed records of experiments, methodologies, and results in compliance with data management and documentation procedures
  • Analyze genomic data using bioinformatics tools and software, interpret the results, and prepare reports for internal stakeholders
  • Stay current with advancements in genomics and related technologies

Knowledge, Skills, and Abilities

• Education and Experience Requirements: Clinical Genomics Technologist II
  • Bachelor's with 3 years of experience OR Master's with 1 year of experience
  • ASCP certification preferred
  • Experience in clinical laboratory preferred
• Well organized, with strong attention to detail and process is required
• Ability to learn new tasks and procedures in appropriate timeframes
• Experience in data management, including laboratory information management systems
• Excellent written and verbal skills as would be required to communicate scientific details and respond to custom inquiries

Pay Range: $52,712 - $84,339

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California),Japan andChina. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visitwww.jax.org.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.