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Forecasting and Analytics, Associate Director (CF)

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Apr 03, 2026

Job Description

General Summary:

Vertex is seeking to hire an Forecasting and Analytics, Associate Director (CF) to join the North America Forecasting, Analytics and Insights team in the Commercial organization. This role will support short to medium term demand forecast, business analytics, KPI tracking and commercial performance reporting for the North America Cystic Fibrosis business. Additionally, this individual will maintain a pulse on critical business questions and regularly synthesize and present performance tracking analytics to appropriate stakeholders.

The ideal candidate must be a skilled and experienced individual contributor, with a demonstrated ability to develop & maintain complex models using both top-down and bottom-up forecasting techniques. This candidate must possess a high degree of attention to detail and accuracy in creating deliverables and must be self-directed in engaging with colleagues. Additionally, this candidate must be able to strategize, collaborate, and manage relationships with cross-functional partners and communicate complex concepts to a wide variety of stakeholders.

Key Duties and Responsibilities:

  • Build, maintain, and continuously improve demand forecast models leveraging top-down and bottom-up approaches to provide an overall forecast and additional detail on depth & breadth of prescribing across customer segments

  • Leverage all available research, data and reporting outputs within the team & cross-functionally to evaluate trends, and synthesize and present performance tracking analytics, to support updates to the commercial LE revenue forecasts

  • Work cross-functionally to coordinate / integrate demand forecast models with gross-to-net, market access, and financial models to ensure alignment & consistency of assumptions

  • Leverage forecast models to support demand & financial modeling for new opportunities under evaluation by the BU

  • Ensure outputs of each forecasting period are clearly communicated to downstream processes (e.g. supply chain) and forecasting data is readily available to required stakeholders within the Cystic Fibrosis BU

  • Collaborate closely with global forecasting team to support annual global long-range planning (LRP) process for global CF business

  • Lead commercial KPI tracking, reporting, and analytics processes end-to-end (e.g., working with IT partners to develop Power BI dashboards, prepare PPT presentations, or other similar materials)

  • Contribute to answering ad-hoc analytics questions as they arise from the BU; work with BU stakeholders to understand their questions and the most appropriate data & analytics approach

  • Develop and leverage a deep understanding of all available data sets, and work with partners to ingest, process, and analyze data for reporting and analytics

  • Work collaboratively with cross-functional stakeholders, including but not limited to US Marketing, Global Marketing, US Market Access, US Finance, and Commercial Sales Operations

  • Contribute to the advancement of forecasting, data analytics and reporting capabilities at Vertex

Knowledge and Skills:

  • Proficiency with complex excel forecast models, and experience integrating forecast models with other cross-functional models

  • Proficiency working with wide array of commercial pharma data sets, including data sets such as IQVIA (or equivalent from different data vendor), patient claims data, and internally generated sales / marketing data (e.g. field call data from CRM)

  • Experience using statistical programming language (e.g., SAS, Python, R) to conduct data analytics

  • Strong analytical and business acumen: intellectual curiosity, motivation and ability to structure problems, diagnose issues and triangulate with multiple approaches to generate actionable analytics to drive strategic decision making

  • Experience working with analytics & forecasting leadership to evaluate & pressure-test assumptions and communicate forecasting outputs to business leadership

  • Ability to quickly and thoughtfully adapt to new and evolving business and planning needs

Education and Experience:

  • Master's degree in a quantitative discipline required (Engineering, Statistics, Economics, Finance, Science) or equivalent experience

  • 7-10 years of experience in the pharmaceutical or biotech industry, 6+ years of insights, forecasting, and/or analytics is required.

Pay Range:

$157,800 - $236,600

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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