Position Title: Scientist III
Work Location: Ridgefield, CT 06877
Assignment Duration: 12 Months
Key Responsibilities:
- Design, develop, and execute functional genomics assays, including CRISPR-based editing (e.g., RNP delivery, Perturb-seq), single-cell sequencing, spatial transcriptomics, and CITE-seq.
- Provide technical guidance and training to research scientists on FGSL technologies and techniques, including assay execution, troubleshooting, and resolution of technical issues;
- Documents and maintains detailed laboratory records in accordance with policies;
- Operates and maintains lab equipment in collaboration with other lab members;
- Assists acquisition of necessary supplies and equipment;
- Defines and performs appropriate QC measures;
- Follows relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field;
- Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation;
- Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports
- Automate processing and results reporting and delivery;
- Reports and treats data with a high level of integrity and ethics.
Qualification & Experience:
- CRISPR assays - Must have personally designed guides, performed transfections/infections, selected edited cells, and validated knockouts/knockins
- Next-generation sequencing (NGS) - Hands-on library preparation experience (not just data analysis)
- Single cell technologies - Personal experience with sample prep, library generation, and quality control
- Standard molecular biology techniques - qPCR, Western blot, cloning, gel electrophoresis
- Cell culture - Proficient in maintaining multiple cell lines, transfections, and sterile technique
- Experience in automation is a plus;
- Able to perform variety of FGS experimental techniques at the same time;
- Demonstrated experience working in a multi-disciplinary and collaborative environment;
- Ability to troubleshoot FGS experiments both individually and as part of a team.
- Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner.
- Master's degree from an accredited institution with 4+ years of experience in molecular, cell biology, or related scientific discipline.
Additional Notes from HM -
- Must have 2 years of Crispr experience.
- Molecular biology, qPCR, western blot. Proficiency in cell culture. Primary cell lines.
- Design guide RNA for a target, order a guide RNA, do the cell culture, grow cells, they do the electroporation, coordinate CRO work, submit samples on behalf of other Tas.
- Them teach them single-cell-seq
- Everyday will be cell culture work; QPCR, western blot
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Spectraforce Technologies
Apr 02, 2026