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Senior Program Manager

GlaxoSmithKline
paid holidays
United States, Massachusetts, Cambridge
Feb 20, 2026
Site Name: South San Francisco 611 Gateway Blvd, Cambridge MA, Seattle Sixth Ave, USA - Pennsylvania - Upper Providence
Posted Date: Feb 20 2026

The Onyx Research Data Tech organization is GSK's Research data ecosystem which has the capability to bring together, analyze, and power

the exploration of data at scale. We partner with scientists across GSK to define and understand their challenges and develop tailored solutions

that meet their needs. The goal is to ensure scientists have the right data and insights when they need it to give them a better starting point for

and accelerate medical discovery. Ultimately, this helps us get ahead of disease in more predictive and powerful ways.

Onyx is a full-stack shop consisting of product and portfolio leadership, data engineering, infrastructure and DevOps, data / metadata / knowledge

platforms, and AI/ML and analysis platforms, all geared toward:

  • Building a next-generation, metadata- and automation-driven data experience for GSK's scientists, engineers, and decision-makers,increasing productivity and reducing time spent on "data mechanics"
  • Providing best-in-class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top-tier talent
  • Aggressively engineering our data at scale, as one unified asset, to unlock the value of our unique collection of data and predictions in real-time

Oversight of the program of work is key to successful execution of this mission. The Onyx Portfolio Management team is accountable for defining,

building, and executing on our internal processes for agile planning and delivery across our entire portfolio. They ensure that the leadership of the

Onyx organization and key partners / stakeholders have a transparent view into our overall progress, and that issues / blockers / misalignments

are raised early before they become major problems. They partner with our product and engineering leadership to ensure our overall ways of

working, including software delivery, are best-in-class and set us up for success.

The Senior Program Manager is accountable for supporting the Onyx Application Engineering vertical with program and project management

needs, ensuring quality in internal standard ways of working including appropriate documentation, resource tracking and capacity planning to

ensure successful program/project delivery. The incumbent partners with Product Managers to devise and execute realistic, achievable and high-

quality plans that describe tasks required to deliver Onyx products across multiple engineering teams. A senior PM is expected to be able to

consistently take a poorly defined problem with a large degree of ambiguity, work it to a well-defined problem / specification, and execute on it at a

high level.

Key Responsibilities

  • Development and management of project plans; driving execution within scope, time and budget which may dynamically evolve to reflect change in customer needs or business constraints.
  • Leading shiprooms and agile sprint ceremonies, project tracking/reporting and managing backlogs with product managers. This to include a single view of each project within the portfolio of work and their interdependencies, establishing effective OKRs, robust documentation and project value/financial tracking.
  • Partner with Onyx engineering leads and product owners to implement good project management discipline (tools and process) across all product deliverables, including use of Jira, Confluence, and similar productivity software
  • Partner with Tech and partners in R&D to ensure that interdependencies are well understood and that all ingredients needed to understand complex multi-organizational work are brought together and presented as a whole. This includes identifying critical path items, milestones and interdependencies across Onyx
  • Defines appropriate tracking measures and building automated comprehensive as well as meaningful reports/dashboards; synthesizing data and insights from across a project or program of work to support teams make informed tactical and strategic decisions
  • Ensure that good risk management practice is embedded within Onyx projects and that risks and opportunities are identified, addressed or that risks requiring collective senior discussion are escalated to the Onyx leadership team
Why You?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Bachelors' degree in IT Program Management, Data Engineering, Computer Science, Software Engineering, or related discipline
  • 6+ years job-related experience with an established track record of Program delivery for software application

  • 4+ years' experience in Agile program/project management, including the use of associated tools such as Jira and Confluence

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Master's degree in IT Program Management, Data Engineering, Computer Science, Software Engineering, or related discipline
  • Demonstrated comfort operating and leading across organizational boundaries a matrixed team

  • Metrics-first mindset

  • Holds project management certifications (PMP, scrum, etc.)

  • Excellent communicator and collaborator

#LI-GSK

* If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $127,050 to $211,750.

The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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