Researcher I

The Department of Pediatrics is seeking a Researcher I to work in the Division of Genetics and Metabolism. This position supports translational biomedical research focused on rare genetic disorders using mouse models and human induced pluripotent stem cell (iPSC)-derived neuronal systems in the laboratory of Dr. Bryn Webb. The researcher will perform and manage wet-bench experimental studies, including characterization of genetically engineered mouse models, stem cell culture and neuronal differentiation, molecular and cellular assays, and data generation to support externally funded research projects. The work will focus on disease modeling in inherited mitochondrial disorders and a genetically defined ataxia syndrome. This role is essential to advancing mechanistic studies of human disease, supporting grant deliverables, and maintaining safe and compliant laboratory operations within a physician-scientist-led research program.

• This position requires work to be completed onsite, at a designated campus work location.

Candidates who demonstrate the following knowledge, skills, and abilities will be given first consideration:

• Ability to work independently in a research laboratory environment and manage multiple ongoing experimental projects.

• Strong organizational skills and attention to detail.

• Identifies concerns and recommends solutions to leadership

• Trains individuals and groups on equipment operations, research protocols, and techniques within a specialized laboratory or research area

• Assists in developing grant applications and proposals to secure research funding

• Collects and analyzes basic research data, conducts experiments and interviews, and documents results according to established policies and procedures

• Assists with the development of research methodologies and procedures

• Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities and assists with publications

School of Medicine and Public Health, Department of Pediatrics, Division of Genetics and Metabolism, Webb Research Group

The Department of Pediatrics at the University of Wisconsin School of Medicine and Public Health is a vibrant academic department comprising more than 230 faculty members in 16 subspecialty divisions. The department promotes and enhances the health of children through outstanding clinical care, exemplary education of pediatric trainees, performance of cutting-edge research, and vigorous advocacy. Our faculty and research staff enjoy a robust infrastructure of services as well as the opportunity to contribute to our world-class research portfolio - since 2015 the department has ranked among the Top 20 pediatrics departments receiving NIH funding, according to Blue Ridge Institute for Medical Research. To provide remarkable health care for everyone in our community, we are committed to fostering a diverse, equitable, and inclusive environment in all aspects of our work. To learn more about the department's work and accomplishments, please visit: https://www.pediatrics.wisc.edu/.

• The starting salary for the position is $50,000 annually; but is negotiable based on experience and qualifications.

• Employees in this position can expect to receive benefits such as generous vacation, holidays, and sick leave; competitive insurances and savings accounts; retirement benefits. For more information, refer to the campus benefits webpage.

• SMPH Faculty /Academic Staff Benefits Flyer 2026

• Hands-on experience with either mouse models or stem cell-based experimental systems.

• Demonstrated experience with mammalian cell culture techniques.

• Experience performing standard molecular biology and biochemical techniques, including DNA/RNA isolation, PCR, gel electrophoresis, and Western blotting.

• Experience maintaining accurate laboratory records and adhering to established laboratory protocols.

• Familiarity with disease modeling in rare genetic, mitochondrial, or neurodevelopmental disorders.

• Experience working with human induced pluripotent stem cells (hiPSCs), including culture, maintenance, and neuronal differentiation OR Experience with prior study of the brain in mouse models (e.g., tissue dissection, brain region isolation, histology, immunohistochemistry).

• Experience with mitochondrial function assays (e.g., OXPHOS analysis, Seahorse metabolic assays).

• Experience with microscopy.

Master's Degree is required; focus in biology, neuroscience, genetics, molecular biology, biomedical sciences, or a related field is required.

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To apply for this position, select either "I am a current employee" or "I am not a current employee" under Apply Now. You will then be prompted to upload your application materials.

Important: The application has only one attachment field. Upload the following documents in that field, either as a single combined file or as multiple files in the same upload area.

• Cover letter

• Resume

Your cover letter should address how your training and experience aligns with the required and preferred qualifications listed above. Application reviewers will rely on these written materials to determine which applicants move forward in the process. References will be requested from final candidates. All applicants will be notified once the search concludes and a candidate is selected.

University sponsorship is not available for this position, including transfers of sponsorship and TN visas. The selected applicant will be responsible for ensuring their continuous eligibility to work in the United States (i.e. a citizen or national of the United States, a lawful permanent resident, a foreign national authorized to work in the United States without the need of an employer sponsorship) on or before the effective date of appointment. This position is an ongoing position that will require continuous work eligibility. If you are selected for this position you must provide proof of work authorization and eligibility to work.

The department will not be able to support a request for a J-1 waiver. If you choose to pursue a waiver and apply for our position, neither the UW nor UWMF will reimburse you for your legal or waiver fees.

Hope Jende, hope.jende@wisc.edu, 608-262-0149

Relay Access (WTRS): 7-1-1. See RELAY_SERVICE for further information.

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