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Exec. Director, Advanced Analytics & Data Science

BioCryst Pharmaceuticals
United States, North Carolina, Durham
4505 Emperor Boulevard (Show on map)
Dec 18, 2025
Description

COMPANY:

At BioCryst, we share a deep commitment to improving the lives of people living with complement-mediated and other rare diseases. For over three decades we've been guided by our passion for not settling for "ordinary" in our quest to develop novel medicines. We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and protein therapeutics, led by the efforts of our team of expert scientists in our Discovery Center of Excellence in Birmingham, Alabama. Our global headquarters is in Durham, North Carolina, our European headquarters is in Dublin, Ireland and our employees span the globe across sites in multiple countries. We are proud of our culture of engagement and accountability that rewards people for innovative thinking and achievement of key objectives. For more information, please visit our website at www.biocryst.com or follow us on LinkedIn and Instagram.

JOB SUMMARY:

The Executive Director, Advanced Analytics and Data Science, will lead BioCryst's advanced analytics strategy, driving a data-driven culture and supporting business decisions across Commercial (Sales, Marketing, Market Access, Patient Services, Managed Markets), Medical Affairs, Health Economics & Outcomes Research (HEOR), and Clinical Development. This leader will have consistent interactions with C-suite executives and oversee a multidisciplinary team, integrating data science, forecasting, and business analytics to deliver actionable insights, innovative methodologies, and strategic recommendations that accelerate BioCryst's growth and impact in rare diseases. #LI-Remote

ESSENTIAL DUTIES & RESPONSIBILITIES:

Strategic Leadership & Vision



  • Set the vision and strategy for the advanced analytics and data science.
  • Lead, mentor, and develop a high-performing analytics team, fostering innovation, collaboration, and continuous improvement.
  • Ensure alignment with the SDIO leadership on overall strategy.


Advanced Analytics and Data Science



  • Oversee the design and implementation of predictive models, machine learning algorithms, and statistical analyses to support business decisions.
  • Direct the evaluation and integration of large-scale datasets, including anonymized patient-level data (APLD), real-world evidence (RWE), claims, and operational data.
  • Develop and implement innovative analytical approaches for insight generation, including data mining, exploration, modeling, deployment, and assessment.
  • Ensure robust data governance, data integrity, and compliance with privacy and regulatory standards, including tokenization and anonymization of patient data.


Forecasting and Business Intelligence



  • Lead the development of forecasting methodologies for Commercial functions, ensuring alignment with business performance updates and strategic goals.
  • Oversee the creation and maintenance of dashboards, reports, and KPIs to inform brand performance, sales projections, and strategic initiatives.
  • Guide the development, alignment, and management of incentive compensation plans for Sales, partnering with Sales Leadership and Marketing.


Cross-Functional Leadership



  • Provide strategic leadership and guidance to Commercial, Medical Affairs, HEOR, Clinical Operations, and SDIO to integrate analytics and insights across the organization.
  • Partner with Medical Affairs and HEOR on data strategy and external communications regarding the value of BioCryst's product portfolio (RWE and RWD).
  • Collaborate with IT, engineering, and strategic operations to design scalable data pipelines and analytics infrastructure.
  • Cultivate and manage strategic partnerships with external vendors and data partners.


Innovation & Continuous Improvement



  • Proactively evaluate and incorporate new data sources, analytical tools, and methodologies to maximize impact.
  • Champion adoption of AI-based tools and advanced analytics platforms.
  • Develop BioCryst's advanced analytics capabilities through continual evaluation and implementation of innovative methodologies and tools.


Team & Project Management



  • Direct the project prioritization, resource allocation, and delivery of analytics and data science team's initiatives.
  • Ensure accuracy, completeness, and timeliness of analytics deliverables.
  • Develop talent and succession plans for the analytics organization.
  • Direct multiple workstreams simultaneously across a breadth of workstreams and functions in a fast-paced environment.


Data Governance & Compliance



  • Ensure proper controls and governance to support and protect key data assets.
  • Oversee integration of disparate data sets to create insights and strategy, with a focus on patient journey and anonymity.
  • Ensure compliance with US and international data privacy and security regulations.



EXPERIENCE & QUALIFICATIONS:



  • Bachelor's degree required; MBA, PhD or other advanced degree strongly preferred
  • 12+ years of experience (or combination of education and experience) in the biotech, pharmaceutical, or related industry is required, with experience in analytics-based roles, forecasting, sales operations
  • Experience leading teams in matrixed organizations and supporting multiple departments
  • Rare disease experience is strongly preferred
  • Experience developing business and sales analytics models and conducting rigorous quantitative analyses
  • Experience working with anonymized patient level data (APLD) and personal identifiable information (PII)
  • A proven track record of helping to translate the analytical output into real business impact and of taking a creative approach to problem solving
  • Experience with 3rd party pharmaceutical data (e.g., IQVIA, Symphony Health, Komodo), claims data and managed care data
  • Experience managing projects and vendors
  • Ability to work collaboratively and handle multiple projects simultaneously in a fast-paced environment
  • Ability to quickly develop ad hoc analyses requested by leadership teams
  • Experience in CRM (e.g., Veeva or Salesforce)
  • Strong verbal and written communication skills; ability to develop and deliver compelling presentations to senior leadership



The statements in this position description are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. The manager may assign additional responsibilities and assignments from time to time.

BioCryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, Veterans status, disability and/or other protected class characteristics. Additionally, BioCryst is committed to achieving its business objectives in compliance with all federal, state and local law.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

This employer is required to notify all applicants of their rights pursuant to federal employment laws.
For further information, please review the Know Your Rights notice from the Department of Labor.
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