Sr Software Engineer

CareDx, Inc. is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers products, testing services, and digital healthcare solutions along the pre- and post-transplant patient journey, and is the leading provider of genomics-based information for transplant patients.

We seek a Senior Software Engineer to contribute to developing clinical data engineering solutions. This role will assist in designing and implementing scalable data pipelines and AI-driven tools to support our mission of improving transplant patient outcomes. The ideal candidate has foundational knowledge in data engineering, OMOP, and natural language processing (NLP), with an interest in cloud computing and precision medicine.

Key Responsibilities:

• Data Architecture & Modeling:
  • Partner with data engineers to design, implement, and optimize data models (star schemas, data vault, etc.).
  • Ensure data quality, consistency, and governance across all pipelines.
• Pipeline & App Development:
  • Collaborate with data scientists to build end-to-end ETL/ELT pipelines using Python, SQL, and orchestration tools (Airflow, Prefect, etc.).
  • Develop interactive data applications and dashboards using Plotly, Bokeh, or similar libraries.
  • Implement LLM-powered agents and conversational interfaces leveraging LlamaIndex, LangChain, and Pydantic Agent.
• Cloud Infrastructure & DevOps:
  • Design, deploy, and maintain cloud resources (compute, storage, networking) primarily in Azure (with AWS/GCP experience).
  • Build and manage CI/CD pipelines (GitHub Actions, Azure DevOps, Jenkins) for code, infrastructure (IaC), and model deployments.
  • Monitor performance and cost; optimize resource utilization.
• Security & Compliance:
  • Apply HIPAA, GDPR, and other relevant regulatory requirements to data handling and platform security.
  • Implement best practices for identity and access management, encryption, audit logging, and vulnerability management.
• Mentorship & Collaboration:
  • Lead code reviews, advocate for best practices (testing frameworks, coding standards, documentation).
  • Mentor junior engineers; drive continuous improvement and knowledge sharing across the team.
  • Participate in agile ceremonies, sprint planning, and stakeholder demos.
• Operational Excellence:
  • Implement logging, monitoring, and alerting for data pipelines and applications using tools like Prometheus, Grafana, or Azure Monitor.
  • Troubleshoot and resolve production incidents; conduct postmortems to drive reliability improvements.
  • Document architecture, runbooks, and development standards.

Basic Qualifications:

• Education & Experience:
  • Bachelor's degree in Computer Science, Engineering, or related field plus 6+ years of professional software engineering experience, OR
  • Master's degree in a relevant discipline plus 3+ years of experience.
• Technical Skills:
  • Programming: Expert in Python and SQL with 3+ years working on relational databases (PostgreSQL, MySQL, SQL Server).
  • Cloud: 3+ years architecting and operating workloads in Azure (preferred), AWS, or Google Cloud.
  • Data Visualization: Hands-on experience with Plotly, Bokeh, or equivalent.
  • LLM Agents: Experience building LLM-based agents using LlamaIndex, LangChain, Pydantic Agent.
  • Data Apps: Track record of building web or desktop data applications (Streamlit, Dash, Flask/Django).
  • CI/CD & IaC: Skilled in pipeline creation and infrastructure-as-code (Terraform, ARM/Bicep, CloudFormation).
  • Security & Compliance: Familiarity with HIPAA, data privacy frameworks, and enterprise security controls.

Preferred Qualifications:

• Prior experience in Biotech, Pharmaceutical, or Diagnostics industries.
• Knowledge of big data platforms (Databricks, Snowflake, Redshift).
• Experience with containerization and orchestration (Docker, Kubernetes).
• Background in data governance, metadata management, or MLOps.
• Experience with real-time streaming frameworks (Kafka, Azure Event Hubs).
• Contributions to open-source data or ML projects.

San Francisco Bay Area:

The anticipated base salary range for candidates who will work in Brisbane, California is $140,000 to $175,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

REMOTE: US only

The anticipated base salary range in the United States is $112,000 to $140,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

Additional Details:

Every individual at CareDx has a direct impact on our collective mission to improve the lives of organ transplant patients worldwide. We believe in taking great care of our people, so they take even greater care of our patients.

Our competitive Total Rewards package includes:

• Competitive base salary and incentive compensation
• Health and welfare benefits including a gym reimbursement program
• 401(k) savings plan match
• Employee Stock Purchase Plan
• Pre-tax commuter benefits
• And more!
• Please refer to our page to view detailed benefits at https://caredx.com/company/careers/
  

In addition, we have a Living Donor Employee Recovery Policy that allows up to 30 days of paid leave annually to a full-time employee who makes the selfless act of donating an organ or bone marrow.

With products that are making a difference in the lives of transplant patients today and a promising pipeline for the future, it's an exciting time to be part of the CareDx team. Join us in partnering with transplant patients to transform our future together.

CareDx, Inc. is an Equal Opportunity Employer and participates in the E-Verify program.

By proceeding with our application and submitting your information, you acknowledge that you have read our U.S. Personnel Privacy Notice and consent to receive email communication from CareDx.

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