Rsch Pro 4-Genetics/Cell Bio

The goal of the Gill Lab at the University of Minnesota is to understand molecular mechanisms that underpin the basic biology of development and aging in the nematode Caenorhabditis elegans. The lab employs various genetic approaches, including CRISPR / Cas9 gene editing, forward and reverse genetics, RNASeq as well as life history trait analysis. Another focus is the development of drug screening approaches to identify compounds that influence lifespan in C. elegans.

In close association with the lab head, the Laboratory manager will be responsible for developing and maintaining institutional biosafety committee (IBC) compliance protocols, managing worm strains, conducting lab supply ordering, training of personnel in laboratory skills and biosafety protocol implementation. In addition to managing lab operations, the Lab Manager will also be involved in principal investigator-directed collaborative and independent research projects, including worm strain generation, collecting and analyzing data, writing results, contributing to written manuscripts and grants.

Duties and Responsibilities:
The distribution of effort between management and research may vary based on lab needs.

30% Lab Operations
* Maintain equipment, track inventory and order reagents related to general lab function and research projects.
* Ensure lab adherence to regulations, training requirements, perform duties as necessary for regulatory compliance.
* Manage lab resources including worm strains and plasmid collections
* Train personnel and undergraduates in laboratory and experimental techniques, record keeping practices and data analysis.

70% Research:
* Independently create and plan experiments based on knowledge and expertise in the field. Collect and complete analysis of data from experiments.
* Implement and optimize new C. elegans techniques and technologies.
* Generate transgenic and CRISPR edited C. elegans strains.
* Assist on collaborative projects as well as perform independent research.
* Implement SOPs for lifespan analysis and chemical screens.

Qualifications (must be on your resume)

Required:

* BA/BS degree plus five years or relevant experience, or a combination of education and relevant work experience to equal at least nine years
* Demonstrated expertise in in vivo proteomic and genetic approaches to study E3 ubiquitin ligases in Caenorhabditis elegans
* Experience investigating novel heterochronic functions of the C. elegans period-related protein LIN-42.
* Demonstrated ability to work independently, make decisions, problem solve, and prioritize research efforts in line with research missions
* Excellent oral and written communication skills
* Excellent organizational skills

Preferred Qualifications:
* C. elegans biology including basic strain maintenance and phenotypic analysis
* Genetic crosses and epistasis analysis
* Generation of transgenic C. elegans by microinjection
* Design and implementation of CRISPR / Cas9 gene editing in C. elegans including deletions, epitope tagging and large insertions
* Molecular cloning
* Immunoprecipitation and co-immunoprecipitation of C. elegans proteins
* Fluorescence microscopy and image analysis of C. elegans, including but not limited to confocal microscopy

Pay Range: $24 - $40/hr; depending on education/qualifications/experience

Time Appointment Category: 75%-100% Appointment (If job description above does not specify appointment or expected weekly hours, assume a 100% appointment.)

Position Type: Civil-Service & Non-Faculty Labor Represented Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).