Senior Research Scientist

The Center for Translational & Computational Neuroimmunology (CTCN), in the Department of Neurology at Columbia University Medical Center (CUMC) is a hub for large-scale translational human studies that integrate rigorous application of advanced laboratory techniques with cutting-edge computational methods. The CTCN includes a Neuroimmunology Core that is part of the national Alzheimer's Disease Research Center network in the U.S., and it specializes in the optimization and deployment of novel experimental platforms to support the projects of CTCN investigators and collaborators involving Alzheimer's, Multiple Sclerosis, neurodegeneration, and immune aging. Currently, we are looking for a new team member to join our research effort as a non-tenure senior research scientist and lead our experimental methods development and application effort in the area of spatially registered data in human and model system central nervous system tissue. In particular, we have been funded by the NIH to develop 3 dimensional atlases of the aging brain to map the effect of age, proteinopathy and cerebral amyloid angiopathy. The candidate will play an important in driving the execution of multiple projects in this grant, the Brain CASCADE project.

The preferred candidate will have strong experience in evaluating and running experimental platforms and laboratory techniques related to high-dimensional data generation from tissue sections. The candidate will also have excellent organizational skills and be able to supervise multiple team members in parallel as different profiles are generated from the same tissue samples. The candidate must therefore have the ability to work effectively in a team environment as all experimental work is deeply integrated with the computational team that include dedicated staff scientists for data pre-processing and QC. Excellent communication and organization skills as well as the ability to work independently are mandatory for this position.

• PhD or equivalent in an immunology-related field sciences and at least three years of postdoctoral or staff scientist experience in a laboratory or research-based environment
• 5 years of experience in industry or academia after completion of the PhD
• Ability to work in a fast-paced environment with demonstrated ability to manage multiple and competing demands and establish priorities.
• Excellent interpersonal, organizational, writing, and verbal communications skills

Preferred Qualifications

• Proficiency in experimental protocols and analysis tools for spatially-registered
• Experience in human or mouse neuroscience and Alzheimer's disease
• Experience with executing milestone-driven projects
• Ability to learn new protocols and platforms