Intern, Formulation Development

BioMarin Pharmaceutical Inc.
sick time
United States, California, Novato
Jan 16, 2025
Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Technical Operations BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. SUMMARY: The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry. Over the course of 10 - 12 weeks our interns gain industry experience while working alongside our talented team on meaningful projects. The Drug Product and Devices Technologies (DPDT) group, a division under the Technical Development organization, is dedicated to BioMarin's mission of developing and commercializing innovative biopharmaceuticals for serious diseases and medical conditions. DPDT is responsible for the development of stable, reproducible, and scalable drug products and devices that meet safety standards for non-clinical, clinical, and commercial use. Furthermore, the group ensures comprehensive chemical and manufacturing process development for small molecules and oligonucleotide drug substances. In addition to in-house product development, DPDT collaborates with contract manufacturing organizations (CMOs) to expedite the development of selected drug product candidates. JOB DESCRIPTION/PROJECT: The selected candidate will join the Drug Product and Devices Technologies group, focusing primarily on non-aqueous based liquid formulation development for peptide molecules or similar compounds. The candidate will work on the following key activities with guidance from their manager: Develop various formulations for peptide molecules Initiate and monitor stability studies in accordance with ICH guidelines Analyze stability samples using various analytical techniques including chromatographic (reverse phase, size exclusion, and ion exchange HPLC), spectrophotometric (UV-VIS), and standard wet chemistry techniques Follow written protocols and assist in revision of working procedures Maintain thorough and timely documentation of experimental protocols and finding Present findings at internal group meetings Required Skills: Basic lab skills including pipetting, using weighing balance Basic understanding of the liquid formulation development Good documentation and communication skills Desired Skills: Familiarity with spectrophotometric, chromatographic, light scattering preferred Experience in liquid formulation development Familiarity with formulation excipients Ability to help with experimental design and analyze experimental datase Qualifications/Eligibility: Pursuing M.S. or PhD in: Pharmaceutical Sciences, Biology, Biochemistry, Chemistry, or Chemical Engineering or related field Must be available to work full time, 40 hours a week. Must be currently enrolled as a full-time student at an accredited U.S. based university or college and enrolled in the fall term after the completion of the internship OR have graduated within 1 year of the start of the program. Must be able to relocate if necessary and work at the designated site for the duration of the internship for on-site, hybrid roles Benefits of a BioMarin Internship: Paid hourly wage, paid company holidays, and sick time Apply skills and knowledge learned in the classroom to on-the-job experiences Comprehensive, value-added project(s) Develop skills specific to your major. Opportunities for professional development by building relationships and learning about other parts of the business. Participate in company all hands meetings, monthly community lunches Corporate office amenities such as: 24/7 on-site gym, coffee truck, snacks Access to Employee Resource Groups Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. In the U.S., the salary range for this position is $30 to $50 per hour, which factors in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.