Research Scientist Medicinal Chemistry

Job Description

General Summary:
Vertex Pharmaceuticals has an exciting opportunity for a Research Scientist in the field of medicinal chemistry. Job responsibilities include the preparation of both single and focused sets of small organic molecules, developing and optimizing synthetic methods, creating and interpreting project-relevant Structure-Activity Relationship (SAR) and problem solving. Candidates must demonstrate an expert understanding of organic reaction mechanisms, formulation of executable synthetic routes, up to date understanding of contemporary synthetic methods as well as an ability to balance rational concepts with creativity which includes the development of new synthetic methodology as needed. The successful candidate will have the ability to work independently and be able to multi-task collaboratively in teams while adapting to rapidly changing needs. A strong desire to grow as a medicinal chemist while maintaining a passion for organic chemistry and the courage to challenge conventional wisdom are essential in this role.

Key Duties and Responsiblities:

• Maintain a high level of productivity in the laboratory setting
• Develops and executes clear synthetic routes using state-of-the-art synthetic methodologies
• Primarily responsible for executing organic syntheses in a timely, efficient, and independent manner
• Create and interpret SAR with a clear understanding of the biological data
• Organize and triage efforts to stay consistent with project priorities
• Clearly and effectively communicate ideas and results (both verbally and in writing) to a broad range of audiences

Knowledge And Skills:

• Designs and executes complex, challenging chemistry experiments
• Demonstrates astute understanding of his/her own discipline and the relevant literature
• Maintains a high level of knowledge related to current developments in the scientic project eld
• Displays proven productivity and experimental creativity, and effective dissemination of ideas
• Demonstrates effective, self-sufcient communication skills, especially in peer-directed presentations
• Demonstrates awareness of other project-related disciplines and an understanding of general concepts and some experimental detail within those areas

Education And Experience:

• Ph.D. (or equivalent degree) in chemistry or related science 0-3 years of relevant post-doctoral employment experience, or
• Master's degree (or equivalent degree) in chemistry or related science and 3+ years of relevant employment experience, or
• Bachelor's degree (or equivalent degree) in chemistry or related science and 6+ years of relevant employment experience
• Demonstrated effective communication skills, both verbal and written
• Ability to navigate and be successful in a fast-paced, highly matrixed work environment
• A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society

Flex Designation:

Flex Eligibility Status:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com